2,2-DICHLOROACETOPHENONE Property

Melting point:

20-21 °C (lit.)

Boiling point:

132-134 °C/13 mmHg (lit.)

Density 

1.34 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.5686(lit.)

Flash point:

>230 °F

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

form 

clear liquid

color 

Colorless to Red to Green

BRN 

1864186

CAS DataBase Reference

2648-61-5(CAS DataBase Reference)

EPA Substance Registry System

Ethanone, 2,2-dichloro-1-phenyl- (2648-61-5)

Safety

Hazard Codes 

Xn,Xi

Risk Statements 

36/37/38

Safety Statements 

26-27-28-36/37/39-7/9

RIDADR 

UN 2810 6.1/PG 2

WGK Germany 

3

RTECS 

AM7175000

TSCA 

Yes

PackingGroup 

II

HS Code 

29147000

Toxicity

mouse,LCLo,inhalation,940mg/m3/10M (940mg/m3),National Defense Research Committee, Office of Scientific Research and Development, Progress Report.Vol. NDCrc-132, Pg. AUG1942,

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

2,2-DICHLOROACETOPHENONE Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS TO SLIGHTLY PINK LIQUID

Uses

2,2-Dichloroacetophenone is a useful research chemical, a PDK inhibitor in an anticancer therapy.

Synthesis Reference(s)

Tetrahedron Letters, 24, p. 527, 1983 DOI: 10.1016/S0040-4039(00)81455-0